Multi-symptom, pain reliever/fever reducer, antihistamine (in nighttime dose only), nasal decongestant. 18 Daytime coated caplets; daytime relief from: Body aches & pain, fever, headache, nasal congestion, sore throat pain, without drowsiness. 6 Nighttime coated tablets; Nighttime relief from: The same symptoms as daytime & more so you can sleep. Day & Night Comtrex Flu Therapy and Fever Relief provides you with two different maximum strength formulas. Comtrex Daytime (orange caplets) is non-drowsy and contains the maximum levels of a non-aspirin analgesic and of the nasal decongestant allowed. Comtrex Nighttime (green tablets), contains the same ingredients plus the maximum level of a antihistamine - so you rest.